Lawrence M Nogee Selected Research

Surface-Active Agents (Surfactants)

1/2022	Child Interstitial Lung Disease in an Infant with Surfactant Protein C Dysfunction due to c.202G>T Variant (p.V68F).
3/2021	Genetic Testing for Neonatal Respiratory Disease.
1/2020	A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency.
1/2020	Neonatal respiratory failure due to novel compound heterozygous mutations in the ABCA3 lipid transporter.
1/2019	Genetic causes of surfactant protein abnormalities.
1/2017	A novel surfactant protein C gene mutation associated with progressive respiratory failure in infancy.
11/2015	A disorder of surfactant metabolism without identified genetic mutations.
11/2014	Natural history of five children with surfactant protein C mutations and interstitial lung disease.
12/2013	Candidate gene analysis of the surfactant protein D gene in pediatric diffuse lung disease.
12/2013	Large ABCA3 and SFTPC deletions resulting in lung disease.

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Lawrence M Nogee Research Topics

Disease

22	Lung Diseases (Lung Disease) 03/2021 - 06/2002
13	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022 - 03/2002
8	Respiratory Insufficiency (Respiratory Failure) 01/2020 - 10/2006
4	Newborn Respiratory Distress Syndrome 09/2013 - 10/2006
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2019 - 01/2004
3	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2019 - 07/2008
3	Surfactant Dysfunction 12/2013 - 06/2004
2	Premature Birth (Birth, Premature) 01/2021 - 01/2020
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2018 - 10/2006
2	Pulmonary Alveolar Proteinosis 11/2010 - 11/2008
1	Neutropenia 01/2021
1	Lymphopenia (Lymphocytopenia) 01/2021
1	COVID-19 01/2021
1	Sudden Infant Death (SID) 09/2020
1	Lung Injury 01/2020
1	Polyhydramnios 01/2020
1	Sepsis (Septicemia) 12/2018
1	Lung Neoplasms (Lung Cancer) 12/2018
1	Cystic Fibrosis (Mucoviscidosis) 12/2018
1	Asthma (Bronchial Asthma) 12/2018
1	Idiopathic Pulmonary Fibrosis 12/2018
1	Pulmonary Arterial Hypertension 12/2018
1	Chronic Obstructive Pulmonary Disease (COPD) 12/2018
1	Hepatomegaly 01/2018
1	Cough 11/2015
1	Dyspnea (Shortness of Breath) 11/2015
1	Hypoxia (Hypoxemia) 11/2015
1	Hypothyroidism 09/2013
1	RDS - infants 12/2012
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 11/2012
1	Amyloid Plaque 02/2012
1	Alveolar capillary dysplasia 03/2010
1	Uniparental Disomy 12/2009
1	Failure to Thrive 11/2008
1	Fibrosis (Cirrhosis) 07/2008
1	Pulmonary Hypertension 09/2007
1	Vascular Diseases (Vascular Disease) 10/2006
1	Congenital Deficiency of Pulmonary Surfactant Protein B 10/2006
1	Inflammation (Inflammations) 06/2004

Drug/Important Bio-Agent (IBA)

32	Surface-Active Agents (Surfactants)IBA 01/2022 - 03/2002
18	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2004
13	Protein CIBA 01/2022 - 03/2002
9	Adenosine Triphosphate (ATP)IBA 01/2019 - 06/2006
4	Transcription Factors (Transcription Factor)IBA 03/2021 - 03/2010
4	Pulmonary Surfactants (Pulmonary Surfactant)IBA 01/2019 - 10/2006
4	IgA receptor (protein B)IBA 12/2009 - 10/2005
2	Complementary DNA (cDNA)IBA 01/2020 - 06/2012
2	Methylprednisolone FDA LinkGeneric 11/2017 - 11/2015
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 11/2017 - 11/2015
2	Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA 11/2010 - 03/2010
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 11/2010 - 11/2008
2	DNA (Deoxyribonucleic Acid)IBA 10/2005 - 03/2005
1	Transaminases (Aminotransferases)IBA 01/2021
1	AntigensIBA 09/2020
1	LipidsIBA 01/2020
1	Progesterone FDA LinkGeneric 01/2020
1	Tocolytic Agents (Tocolytics)IBA 01/2020
1	Thyroid Nuclear Factor 1IBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 12/2018
1	CollagenIBA 01/2018
1	Oxygen (Dioxygen)IBA 11/2015
1	SteroidsIBA 11/2015
1	Azithromycin (Zithromax)FDA LinkGeneric 11/2015
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 06/2014
1	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 12/2013
1	Pyridinolcarbamate (P23)IBA 12/2012
1	Pharmaceutical PreparationsIBA 11/2012
1	Peptides (Polypeptides)IBA 02/2012
1	5' Untranslated Regions (5' UTR)IBA 07/2010
1	Telomerase (Telomerase Reverse Transcriptase)IBA 03/2010
1	Phospholipids (Phosphatides)FDA LinkGeneric 07/2009
1	Adenosine (Adenocard)FDA LinkGeneric 07/2008
1	Isoleucine (L-Isoleucine)FDA Link 08/2007
1	Threonine (L-Threonine)FDA Link 08/2007
1	Codon (Codons)IBA 08/2007
1	Pulmonary Surfactant-Associated ProteinsIBA 01/2007

Therapy/Procedure

4	Therapeutics 11/2012 - 09/2007
2	Lung Transplantation 01/2019 - 10/2006
1	Cesarean Section (Caesarean Section) 01/2021
1	Artificial Respiration (Mechanical Ventilation) 01/2021
1	Pessaries 01/2020
1	Precision Medicine 12/2018
1	Activities of Daily Living (ADL) 11/2014
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 11/2012
1	Transplantation 10/2006